Does G-spot exist?

We will discuss “Verification of Anatomy and Histologic New Discovery of the G-spot Complex” by Ostrzenski and co-workers from 30 July 2014. It is important you read the mini-commentaries published alongside with this paper for a balanced discussion.

*This paper and its accompanying commentaries will be made free-to-view for four weeks from 19 May 2014. 

Start date: 30 July 2014 (the discussion will open for 7 days)

First hosted discussion session(s) starts at: BST 7pm (UK time)

Host: @BlueJCHost

Platforms: Twitter

The Blue Journal Club is an international journal club on women’s health research based on Twitter (as @BlueJCHost). We start our conversation on the last Wednesday of each month and use the hashtag #BlueJC for our tweets. Simply add this hashtag (“#BlueJC”) to each tweet and we will capture it. Each #BlueJC opens for 7 days with an advertised start time.

All BJOG #BlueJC papers also have complementary slide sets suitable for face-to-face journal clubs with your local colleagues. You can access the slide set of this paper here (data S1).

The discussion points are attached below (quoted from the published manuscript)


A 40-year-old businesswoman who has recently undergone surgery and adjuvant chemotherapy for breast cancer was referred to your menopause clinic because of climacteric symptoms. She is at high risk of recurrence and hormone replacement therapy was not recommended.

During her follow-up appointment, she describes difficulties in having intercourse, including vaginal dryness, lack of desire for intimacy and orgasm. Having tried a number of complementary therapies and relaxation techniques, she is now considering cosmetic genital surgery to improve sexual satisfaction. How would you counsel her?

 Description of research

Participants Eight consecutive fresh human female cadavers
Intervention Anterior vaginal wall dissections. Microdissections were stained with haematoxylin and eosin (H&E)
Comparison Two subjects had further immunohistochemical staining (SMA, CD31, D2-40, S100) and the results compared with H&E staining
Outcomes A neurovascular structure in the anterior vaginal wall was identified in each cadaver dissected
Study design A descriptive study

Discussion Points:

  • How is female sexual dysfunction diagnosed and classified?
  • How prevalent is female sexual dysfunction? How is it managed?
  • What is Gräfenberg area (G-spot)? How did authors in this study identify G-spot anatomically?
  • What are the potential sources of bias in this study?
  • What is the evidence supporting the neurovascular structure identified is related to sexual pleasure?
  • List all genital operations for promoting sexual pleasure you are aware of.
  • Explain the differences between cosmetic genital operations and female genital mutilation.
  • After reviewing this paper and its linked mini-commentary, do you think G-spot exists?

Suggested reading

Shifren JL, Monz BU, Russo PA, Segreti A, Johannes CB. Sexual problems and distress in United States women: prevalence and correlates. Obstet Gynecol. 2008  Nov;112(5):970-8.

Buster JE. Managing female sexual dysfunction. Fertil Steril. 2013 Oct;100(4):905-15.


For those who want to understand hashtags, this may be a useful guide. For an introduction to #BlueJC, please refer to BJOG 2013;120:657–60. Follow @BlueJCHostthis blog and our Facebook page to receive news about #BlueJC.