We will discuss “A randomised controlled trial of outpatient compared with inpatient cervical ripening with prostaglandin E2 (OPRA study)“ by Wilkinson and co-workers from 29 October 2014 for 7 days.
*This paper will be made free-to-view on 20 October 2014.
Start date: 29 October 2014 (the discussion will open for 7 days)
First hosted discussion session(s) starts at: GMT 7pm (UK time)
The Blue Journal Club is an international journal club on women’s health research based on Twitter (as @BlueJCHost). We start our conversation on the last Wednesday of each month and use the hashtag #BlueJC for our tweets. Simply add this hashtag (“#BlueJC”) to each tweet and we will capture it. Each #BlueJC opens for 7 days with an advertised start time. All BJOG #BlueJC papers also have complementary slide sets suitable for face-to-face journal clubs with your local colleagues. You can access the slide set of this paper here (data S1).
The discussion points are attached below (quoted from the published manuscript)
A woman, G2P1, had induction of labour for post-date for first child. She is now 41+3 weeks. She has no other risk factors. She asked, “my last induction took days to work, can I go home after “the gel” and come in when I am in labour?”
Description of research
|Participants||Women with uncomplicated term pregnancies, scheduled for induction of labour for post-dates or social reasons|
|Intervention||Outpatient management during cervical ripening with prostaglandin E2 gel|
|Comparison||Inpatient management during cervical ripening with prostaglandin E2 gel|
|Outcomes||Syntocinon usage, obstetric interventions, maternal and neonatal complications|
|Study design||Randomised controlled trial (1:1)|
- Critically appraise this study using the RCT Critical Appraisal Sheet by the Centre for Evidence-based Medicine (http://bit.ly/1ailHBm).
- Has the lack of blinding affected the internal and external validity of this clinical trial?
- Was syntocinon usage an appropriate outcome for the clinical question raised?
- Approximately half of the women did not receive the allocated intervention. How did it affect the interpretation of the results?
- What could have been done to ensure the participants will receive their allocated intervention?
- Can you summarise the available evidence in a single sentence? Is it strong enough to change your practice? (Data S1)
For those who want to understand hashtags, this may be a useful guide. For an introduction to #BlueJC, please refer to BJOG 2013;120:657–60. Follow @BlueJCHost, this blog and our Facebook page to receive news about #BlueJC.