Who should get HPV vaccines in low-resource settings?

We will discuss “The value of male HPV vaccination in preventing cervical cancer and genital warts in a low resource setting” by Sharma and co-workers from 25 November 2015 for 7 days.

*This paper will be made FREE-TO-VIEW on 16 November 2015.

We are now on LinkedIn too: http://linkd.in/1BVrpad (simply ask to join)!

Start date: 25 November 2015 (the discussion will open for 7 days between 25 November to 2 December 2015)

First hosted discussion session(s) starts at: GMT 7pm (UK time)

Host: @BlueJCHost

Platforms: TwitterLinkedIn and Weibo

BJOG_BlueJC_160x600WebBanner_Mar15_(reoriented)_3The Blue Journal Club is an international journal club on women’s health research based on Twitter (as @BlueJCHost). We start our conversation on the last Wednesday of every month and use the hashtag #BlueJC for our tweets. Simply add this hashtag (“#BlueJC”) to each tweet and we will capture it. Each #BlueJC opens for 7 days with an advertised start time. All BJOG #BlueJC papers also have complementary slide sets suitable for face-to-face journal clubs with your local colleagues. You can access the slide set of this paper here (find the title paper and click on the “discussion point” tab).

The discussion points are attached below (quoted from the published manuscript)


At a conference on cervical cancer prevention, a speaker presented data on the cost-effectiveness of HPV vaccination for girls in Thailand (BJOG. 2012;119(2):166-76). An audience asked, “Would vaccinating both boys and girls be better than vaccinating girls only?”.

Description of research

Participants Male and female population (≥ 9 years old) in South Vietnam
Intervention HPV vaccination for both male and female
Comparison HPV vaccination for female only
Outcomes Economical costs, estimates of cervical cancer and genital warts incidence, mortality and quality-adjusted life years (QALYS)
Study design Economic evaluation using mathematical models

Discussion Points

  • What are the incidence of cervical cancer, uptake rate of cervical screening and coverage of HPV vaccine in your country?
  • What is GAVI Alliance? How does it achieve its goals?
  • What are the advantages and disadvantages of using a mathematical model to address this research question? Are there alternatives?
  • What is the purpose of sensitivity analysis in economical evaluations?
  • What is your interpretation of the results presented? Where may the results be generalisable?
  • What are the factors influencing how policy makers utilise findings of economical evaluations?
  • How can researchers maximise the potential of their research being utilised for health policy decision-making?
  • Should we give HPV vaccines to all boys in LMICs?

Suggested reading

  • Critical Appraisal Skills Programme checklist for economical evaluation. http://bit.ly/1EX0KXE
  • Cohen DJ, Reynolds MR. Interpreting the results of cost-effectiveness studies. J Am Coll Cardiol. 2008 Dec 16;52(25):2119-26.
  • Linhares IM, Witkin SS. HPV vaccination: unanswered questions remain. BJOG. 2015 Jan;122(1):118.
  • Gold M. Pathways to the use of health services research in policy. Health Serv Res. 2009 Aug;44(4):1111-36.
  • Haynes AS, Gillespie JA, Derrick GE, Hall WD, Redman S, Chapman S, Sturk H. Galvanizers, guides, champions, and shields: the many ways that policymakers use public health researchers. Milbank Q. 2011 Dec;89(4):564-98.

For those who want to understand hashtags, this may be a useful guide. For an introduction to #BlueJC, please refer to BJOG 2013;120:657–60. Follow @BlueJCHostthis blog and our Facebook page to receive news about #BlueJC.

One thought on “Who should get HPV vaccines in low-resource settings?

  1. Perhaps focus on the healthcare budget in resource poor setting and the allocation per patient per year..and where the priority spending is and affordability!!

Comments are closed.